Multimodality treatment of extra-visceral soft tissue sarcomas M0 state of the art and trends
Identifieur interne : 00C553 ( Main/Exploration ); précédent : 00C552; suivant : 00C554Multimodality treatment of extra-visceral soft tissue sarcomas M0 state of the art and trends
Auteurs : M. Lise [Italie] ; C. R. Rossi [Italie] ; S. Alessio [Italie] ; M. Foletto [Italie]Source :
- European Journal of Surgical Oncology [ 0748-7983 ] ; 1995.
English descriptors
- KwdEn :
Abstract
We here outline principles and trends in the treatment of soft tissue sarcomas without distant metastases (MO). Over the last 15 years significant advances have been made in the diagnostic imaging and histological classification of these tumors as well as in their treatment. Magnetic resonance imaging (MRI) has essentially replaced computerized tomography (CT) for the evaluation of the local growth pattern, although the latter is still preferred for the detection of pulmonary metastases. Immunohistochemistry techniques and electron microscopy have improved the histological diagnosis, although the results obtained should always be interpreted in the context of routine light microscopy. Adequate surgical resection and radiotherapy can reduce the incidence of local recurrence, which is still high for head-neck and retroperitoneal sarcomas. Limb-sparing surgery in combination with irradiation and/or intra-arterial or perfusion chemotherapy is considered the treatment of choice in 90% of limb sarcomas, with a local recurrence rate of less than 20%. New radiotherapeutical techniques and anti-neoplastic agents are now under investigation in an attempt to improve local control. There is also a need for a more effective adjuvant chemotherapy. Randomized clinical trials using doxorubicin/ifosfamide and growth factors are now underway.
Url:
DOI: 10.1016/S0748-7983(95)90039-X
Affiliations:
Links toward previous steps (curation, corpus...)
- to stream Istex, to step Corpus: 001214
- to stream Istex, to step Curation: 001214
- to stream Istex, to step Checkpoint: 004810
- to stream Main, to step Merge: 00CE69
- to stream Main, to step Curation: 00C553
Le document en format XML
<record><TEI wicri:istexFullTextTei="biblStruct"><teiHeader><fileDesc><titleStmt><title xml:lang="en">Multimodality treatment of extra-visceral soft tissue sarcomas M0 state of the art and trends</title><author><name sortKey="Lise, M" sort="Lise, M" uniqKey="Lise M" first="M." last="Lise">M. Lise</name></author><author><name sortKey="Rossi, C R" sort="Rossi, C R" uniqKey="Rossi C" first="C. R." last="Rossi">C. R. Rossi</name></author><author><name sortKey="Alessio, S" sort="Alessio, S" uniqKey="Alessio S" first="S." last="Alessio">S. Alessio</name></author><author><name sortKey="Foletto, M" sort="Foletto, M" uniqKey="Foletto M" first="M." last="Foletto">M. Foletto</name></author></titleStmt><publicationStmt><idno type="wicri:source">ISTEX</idno><idno type="RBID">ISTEX:277ED45162ADA48D2D7EAE2BF4CC2F5CF80B6B4C</idno><date when="1995" year="1995">1995</date><idno type="doi">10.1016/S0748-7983(95)90039-X</idno><idno type="url">https://api.istex.fr/document/277ED45162ADA48D2D7EAE2BF4CC2F5CF80B6B4C/fulltext/pdf</idno><idno type="wicri:Area/Istex/Corpus">001214</idno><idno type="wicri:explorRef" wicri:stream="Istex" wicri:step="Corpus" wicri:corpus="ISTEX">001214</idno><idno type="wicri:Area/Istex/Curation">001214</idno><idno type="wicri:Area/Istex/Checkpoint">004810</idno><idno type="wicri:explorRef" wicri:stream="Istex" wicri:step="Checkpoint">004810</idno><idno type="wicri:doubleKey">0748-7983:1995:Lise M:multimodality:treatment:of</idno><idno type="wicri:Area/Main/Merge">00CE69</idno><idno type="wicri:Area/Main/Curation">00C553</idno><idno type="wicri:Area/Main/Exploration">00C553</idno></publicationStmt><sourceDesc><biblStruct><analytic><title level="a" type="main" xml:lang="en">Multimodality treatment of extra-visceral soft tissue sarcomas M0 state of the art and trends</title><author><name sortKey="Lise, M" sort="Lise, M" uniqKey="Lise M" first="M." last="Lise">M. Lise</name><affiliation wicri:level="4"><country xml:lang="fr">Italie</country><wicri:regionArea>Instituto di Clinica Chirurgica II, Università di Padova, via Giustiniani, 2, 35128 Padova</wicri:regionArea><orgName type="university">Université de Padoue</orgName><placeName><settlement type="city">Padoue</settlement><region type="region" nuts="2">Vénétie</region></placeName></affiliation></author><author><name sortKey="Rossi, C R" sort="Rossi, C R" uniqKey="Rossi C" first="C. R." last="Rossi">C. R. Rossi</name><affiliation wicri:level="4"><country xml:lang="fr">Italie</country><wicri:regionArea>Instituto di Clinica Chirurgica II, Università di Padova, via Giustiniani, 2, 35128 Padova</wicri:regionArea><orgName type="university">Université de Padoue</orgName><placeName><settlement type="city">Padoue</settlement><region type="region" nuts="2">Vénétie</region></placeName></affiliation></author><author><name sortKey="Alessio, S" sort="Alessio, S" uniqKey="Alessio S" first="S." last="Alessio">S. Alessio</name><affiliation wicri:level="4"><country xml:lang="fr">Italie</country><wicri:regionArea>Instituto di Clinica Chirurgica II, Università di Padova, via Giustiniani, 2, 35128 Padova</wicri:regionArea><orgName type="university">Université de Padoue</orgName><placeName><settlement type="city">Padoue</settlement><region type="region" nuts="2">Vénétie</region></placeName></affiliation></author><author><name sortKey="Foletto, M" sort="Foletto, M" uniqKey="Foletto M" first="M." last="Foletto">M. Foletto</name><affiliation wicri:level="4"><country xml:lang="fr">Italie</country><wicri:regionArea>Instituto di Clinica Chirurgica II, Università di Padova, via Giustiniani, 2, 35128 Padova</wicri:regionArea><orgName type="university">Université de Padoue</orgName><placeName><settlement type="city">Padoue</settlement><region type="region" nuts="2">Vénétie</region></placeName></affiliation></author></analytic><monogr></monogr><series><title level="j">European Journal of Surgical Oncology</title><title level="j" type="abbrev">YEJSO</title><idno type="ISSN">0748-7983</idno><imprint><publisher>ELSEVIER</publisher><date type="published" when="1995">1995</date><biblScope unit="volume">21</biblScope><biblScope unit="issue">2</biblScope><biblScope unit="page" from="125">125</biblScope><biblScope unit="page" to="135">135</biblScope></imprint><idno type="ISSN">0748-7983</idno></series></biblStruct></sourceDesc><seriesStmt><idno type="ISSN">0748-7983</idno></seriesStmt></fileDesc><profileDesc><textClass><keywords scheme="KwdEn" xml:lang="en"><term>adjuvant therapy</term><term>diagnosis</term><term>soft tissue sarcomas</term><term>surgery</term></keywords></textClass><langUsage><language ident="en">en</language></langUsage></profileDesc></teiHeader><front><div type="abstract" xml:lang="en">We here outline principles and trends in the treatment of soft tissue sarcomas without distant metastases (MO). Over the last 15 years significant advances have been made in the diagnostic imaging and histological classification of these tumors as well as in their treatment. Magnetic resonance imaging (MRI) has essentially replaced computerized tomography (CT) for the evaluation of the local growth pattern, although the latter is still preferred for the detection of pulmonary metastases. Immunohistochemistry techniques and electron microscopy have improved the histological diagnosis, although the results obtained should always be interpreted in the context of routine light microscopy. Adequate surgical resection and radiotherapy can reduce the incidence of local recurrence, which is still high for head-neck and retroperitoneal sarcomas. Limb-sparing surgery in combination with irradiation and/or intra-arterial or perfusion chemotherapy is considered the treatment of choice in 90% of limb sarcomas, with a local recurrence rate of less than 20%. New radiotherapeutical techniques and anti-neoplastic agents are now under investigation in an attempt to improve local control. There is also a need for a more effective adjuvant chemotherapy. Randomized clinical trials using doxorubicin/ifosfamide and growth factors are now underway.</div></front></TEI><affiliations><list><country><li>Italie</li></country><region><li>Vénétie</li></region><settlement><li>Padoue</li></settlement><orgName><li>Université de Padoue</li></orgName></list><tree><country name="Italie"><region name="Vénétie"><name sortKey="Lise, M" sort="Lise, M" uniqKey="Lise M" first="M." last="Lise">M. Lise</name></region><name sortKey="Alessio, S" sort="Alessio, S" uniqKey="Alessio S" first="S." last="Alessio">S. Alessio</name><name sortKey="Foletto, M" sort="Foletto, M" uniqKey="Foletto M" first="M." last="Foletto">M. Foletto</name><name sortKey="Rossi, C R" sort="Rossi, C R" uniqKey="Rossi C" first="C. R." last="Rossi">C. R. Rossi</name></country></tree></affiliations></record>Pour manipuler ce document sous Unix (Dilib)
EXPLOR_STEP=$WICRI_ROOT/Wicri/Sante/explor/LymphedemaV1/Data/Main/Exploration
HfdSelect -h $EXPLOR_STEP/biblio.hfd -nk 00C553 | SxmlIndent | more
Ou
HfdSelect -h $EXPLOR_AREA/Data/Main/Exploration/biblio.hfd -nk 00C553 | SxmlIndent | more
Pour mettre un lien sur cette page dans le réseau Wicri
{{Explor lien
|wiki= Wicri/Sante
|area= LymphedemaV1
|flux= Main
|étape= Exploration
|type= RBID
|clé= ISTEX:277ED45162ADA48D2D7EAE2BF4CC2F5CF80B6B4C
|texte= Multimodality treatment of extra-visceral soft tissue sarcomas M0 state of the art and trends
}}
| This area was generated with Dilib version V0.6.31. |  |